As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Martinez-Sobrido, Luis
Funded by
University of Texas Health Science Center at San Antonio
Collaborating Institutions
University of Texas Health Science Center San Antonio
We hypothesize that SARS-CoV-2 RNA viral mediated infection impacts cardiomyocyte mitochondrial function that results in cardiomyopathy, heart failure, and high mortality.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Regeneron Pharmaceuticals, Inc.
The purpose of this project is to test monoclonal antibodies in a neutralization assay with SARS-CoV-2 virus to generate IC50 values.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Leopold Wager, Chrissy M
M. tuberculosis, which causes the worldwide global health problem tuberculosis (TB), is transmitted human to human via the airborne route into lung alveoli and ultimately exploits and grows in host macrophages. We seek to understand the cell signaling pathways initiated by infection of human macrophages with M. tuberculosis that lead to disease. Increased understanding of how macrophages are susceptible to M. tuberculosis is expected to aid in the development of host-directed therapies for TB.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Apicella, Alfonso
Muzzio, Isabel
Funded by
Natl Inst of Health
Cortical function is characterized by the dynamic interplay of two major forces: excitation and inhibition. A current belief is that dysfunction of inhibition. mediated by local GABAergic interneurons. leads to a wide range of neurological diseases such as epilepsy. autism. schizophrenia. PTSD. A well-established principle of the cortical circuit organization is that inhibition is local while excitation is both local and long-range; however. this ignores that inhibition may be long-range as well.