The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Boyer, Thomas G
Funded by
NIH-CHILD HEALTH & HUMAN DEVELOPMENT
Collaborating Institutions
Chicago
Uterine leiomyomas (LM; fibroids) are monoclonal neoplasms of the myometrium (MM) and represent themost frequent tumors in women worldwide. Although benign, they nonetheless account for significantgynecologic and reproductive dysfunction.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Hu, Yanfen
Funded by
NIH-NATIONAL CANCER INSTITUTE
The tumor suppressor BRCA1 plays an important role in the homologous recombination (HR) pathwayof DNA double strand break (DSB) repair. From a mechanistic perspective, BRCA1 facilitates recruitment ofnucleases required for end resection, the commitment step in HR repair, yet paradoxically, BRCA1 has beenshown to inhibit the nuclease activity in vitro. It is unclear how nuclease-recruiting and -inhibiting activities ofBRCA1 can be reconciled in HR repair.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Kaklamani, Virginia G
Funded by
NIH-NATIONAL CANCER INSTITUTE
The San Antonio Breast Cancer Symposium (SABCS) is a five day international symposium thatprovides state-of-the-art information on translational research in breast cancer both for basicscientists and clinicians who work directly with patients.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Sun, Luzhe
Funded by
NIH-NATIONAL CANCER INSTITUTE
This competing renewal application requests a second five-year support by the Ruth Kirschstein NationalResearch Service Award (T32) for our ?Cancer Biology Training Program? based at the University of TexasHealth Science Center at San Antonio (UTHSCSA), a Hispanic-Serving Institution.
