As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Olena Shtanko
Funded by
NIH
Collaborating Institutions
University of Iowa
We will be responsible for BSL4 experiments involving Ebola virus infection of treated and untreated murine macrophages.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Tumanov, Alexei V
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Campylobacter is a major human pathogen that infects an estimated 2.5 million people each year resulting in anestimated $1.9 billion economic loss in the U.S. Campylobacter jejuni is a common human enteric pathogen thatcauses acute enterocolitis and increases the risk of developing long-term intestinal dysfunction such as post-infectious irritable bowel syndrome. The innate immune mechanisms responsible for intestinal pathology in C.jejuni-induced colitis are still poorly understood.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Bunnik, Evelien M
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Malaria remains a significant contributor to the global burden of disease. In endemic regions, malaria mostlyaffects children. Older individuals are protected from disease by an immune response against the parasite?sblood stage. Eliciting a protective immune response in children by vaccination would significantly reducemalaria morbidity and mortality. Antibodies are a critical component of such protection. A strong correlationexists between antibodies against merozoite antigens and a reduction in malaria incidence.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Zhang, Nu
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Infectious diseases pose a significant public health burden, accounting for nearly one-fifth of deaths globallyper annum. Most infections are initiated from a restricted mucosal tissue, such as the intestine. To fightintestinal infections, gut-resident immune cells are superior to circulating ones. There is a surge of recentinterest in tissue-resident memory T (TRM) cells that have been shown to be a critical adaptive immunecomponent of mucosal immunity. These cells have been flagged as an ideal cell population to be generated inT cell-based vaccines.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Bunnik, Evelien M
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Malaria remains a significant contributor to the global burden of disease. In endemic regions, malaria mostlyaffects children. Older individuals are protected from disease by an immune response against the parasite?sblood stage. Eliciting a protective immune response in children by vaccination would significantly reducemalaria morbidity and mortality. Antibodies are a critical component of such protection. A strong correlationexists between antibodies against merozoite antigens and a reduction in malaria incidence.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Zhang, Nu
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Infectious diseases pose a significant public health burden, accounting for nearly one-fifth of deaths globallyper annum. Most infections are initiated from a restricted mucosal tissue, such as the intestine. To fightintestinal infections, gut-resident immune cells are superior to circulating ones. There is a surge of recentinterest in tissue-resident memory T (TRM) cells that have been shown to be a critical adaptive immunecomponent of mucosal immunity. These cells have been flagged as an ideal cell population to be generated inT cell-based vaccines.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Patterson, Thomas F
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Collaborating Institutions
UCLA
This contract provides for the development and standardization of animal models for infectious diseases, and may include efficacy testing of candidate products.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Patterson, Thomas F
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Collaborating Institutions
UCLA
This contract provides for the development and standardization of animal models for infectious diseases, and may include efficacy testing of candidate products.