Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Hsieh, Jenny
Funded by
UTSA VPR Office
The `opioid epidemic' is one of the most significant health issues facing this country today with rates of opioid-associated deaths up 200% since 2000. This epidemic is also taking its toll on pregnant women and their babies, with an annual average of ~21,000 pregnant women ages 15 to 44 who have misused opioids this past month. Infants who have been exposed to opioid drugs exhibit an increased risk of neurological and behavioral consequences.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Marinkovic, Milos
Funded by
NIH-DENTAL & CRANIOFACIAL RESEARCH
Adipose tissue-derived mesenchymal stem cells (AD-MSCs) have the potential to serve as a critical toolfor bone tissue engineering as their relatively high frequency in the body can provide the exceedingly largenumbers of cells required for regenerative therapies. Unfortunately, many studies have shown that AD-MSCshave considerably less osteogenic potential than other types of stem cells. Our group has developed an invitro-produced extracellular matrix (ECM) that recapitulates specific attributes of the native bone marrow (BM-)and adipose (AD-) microenvironment.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Yeh, Chih-Ko
Funded by
NIH-DENTAL & CRANIOFACIAL RESEARCH
Collaborating Institutions
UTSA
Saliva is an important defense mechanism for protecting oral health. Salivary gland (SG) hypofunctionresults in uncontrolled and severe oral diseases that lead to severely compromised quality of life. SGsare highly differentiated and have little regenerative capacity once they are destroyed by therapy ordisease (e.g. radiation therapy or autoimmune Sjgren?s syndrome). Therefore, the development ofstrategies for preserving or regenerating the secretory function of SGs is essential for successfulmanagement of these patients.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Marinkovic, Milos
Funded by
NIH-DENTAL & CRANIOFACIAL RESEARCH
Adipose tissue-derived mesenchymal stem cells (AD-MSCs) have the potential to serve as a critical toolfor bone tissue engineering as their relatively high frequency in the body can provide the exceedingly largenumbers of cells required for regenerative therapies. Unfortunately, many studies have shown that AD-MSCshave considerably less osteogenic potential than other types of stem cells. Our group has developed an invitro-produced extracellular matrix (ECM) that recapitulates specific attributes of the native bone marrow (BM-)and adipose (AD-) microenvironment.
