As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
Battelle
The mission of the TxBiomed component is to generate the Marburg virus and propagate it, determine the virus' consensus sequence, experimentally determine the LD50 of guinea pig adapted Angolan Marburg virus, and evaluate the immunogenicity and efficacy of Marburg and Ebola Zaire VLPs monovalent vaccines when administered in two different adjuvants to guinea pigs and Non-Human Primates.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Anderson, Timothy J. C.
Funded by
NIH-PMS
Collaborating Institutions
University of Notre Dame
Gene copy number variation (CNV) is ubiquitous in eukaryotic genomes and the resultant dosage changes can play an important role in determining phenotype. We aim to define the extent, evolutionary dynamics and functionality of CNV in the malaria parasite genome (Plasmodium falciparum). To achieve this we will use comparative genomic hybridization (cGH) which provides an efficient tool for assaying both CNV and single nucleotide polymorphism (SNP) and is particularly effective in haploid genomes.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Fisher BioServices
TxBiomed will furnish the necessary services, qualified personnel, material, equipment and facilities to perform vaccine testing using the MVA-BN-Marv vaccine against 3 viruses.
