Major Goal: The goal of this grant application is to produce clinical grade human neural stem cells from embryonic stem cells and to demonstrate their long-term safety and efficacy in a rodent and a nonhuman primate model (marmoset) of acute focal traumatic brain injury (TBI).

Acquisition and deployment of the CrimeEye video surveillance system with Genetec video analytics that will allow our security team to maximize their efforts to keep our campus secure by having better situational awareness through enhanced monitoring, verification and validation of threats improving security response times.

This major goal of this funding is to outfit the Pathology Unit of SNPRC with a new chemistry analyzer, a new slide stainer and coverslipper, as well as seeks to purchase a state of the art whole slide scanner, which will provide a significant upgrade to research capabilities supported by Texas Biomed.

Core instrumentation for the Biology Core to expand the flow cytometry capabilities.

The purpose of this grant is for the purchase of a Confocal Microscope for Core Research Support project.

The major goal is to increase primate holding capacity for the P51 base grant.

BioBridge Global has been named one of two Prototype of the Year Award winners by the Medical Technology Enterprise Consortium (MTEC) for work done following a $7.8 million MTEC grant for the development of large-scale manufacturing capabilities for clinical-grade adult stem cells.

The award was presented at the MTEC Annual Meeting on March 4.

The objective of this proposal is to develop and characterize a novel Nanopore Microneedle Array that will enable cell transformation. Transformation will be enacted on 3D tissue volumes through cell electroporation and electrophoretic introduction of genetic material, causing a change in cell phenotype. In the proposal, the initial fabrication, testing, and proof-of-concept is described. Fabrication will be conducted at the Microelectronics Research Center on the J. J. Pickle Research Campus of the University of Texas at Austin.

Southwest Research Institute has received new funding from the Medical Technology Enterprise Consortium (MTEC) and the Food and Drug Administration (FDA) to use an SwRI-developed bioreactor to propagate cells for personalized regenerative medicine applications. A $3 million MTEC program will demonstrate stem cell manufacturing, and a $2.3 FDA contract is funding CAR T-cell production.

One of the most important goals of dentistry and the NIDCR/NIH is to generate a whole ?Bio-Tooth?. Dentin is a critical structural component of tooth. Although it has made great progress ofdentin development benefit for numerous hereditary syndromes and chromosomal anomalies,many gaps have been remained.