As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
The purpose of this study will be to evaluate the immunogenicity and protective efficacy of pGX9501 (INO-4800) at a 0.5mg and 1 mg dose in the Rhesus macaque model of SARS-CoV-2 challenge.						
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Daadi, Marcel M
Collaborating Institutions
University of California Irvine
Major Goal: The goal of this grant application is to produce clinical grade human neural stem cells from embryonic stem cells and to demonstrate their long-term safety and efficacy in a rodent and a nonhuman primate model (marmoset) of acute focal traumatic brain injury (TBI).
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Ebrahimi, Diako
Funded by
William & Ella Owens Medical Research Foundation
Our DNA contains many sequences of ancient viral origin. Activation of these viruses can trigger components of our immune system such as APOBEC3 enzymes, which in turn can induce DNA mutation and damage. We aim to use a combined computational/experimental approach to reveal the role of our internal viral sequences in cancer mutations.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Mohan, Mahesh
Identify epigenetic mechanisms associated with monocyte/microglia activation associated with HIV associated neurocognitive disorder using the SIV-rhesus macaque model. In addition, we will use cannabinoids to suppress inflammation and determine the epigenetic mechanisms underlying its anti-inflammatory effects.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Kulkarni, Viraj
Funded by
Particle Inc.
In vivo testing and evaluation of viral replication on first screening of ASO #11-30.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Shtanko, Olena
The objective of this proposal is to interrogate the interaction(s) between EBOV and macrophage podosomes, mechanosensitive adhesive structures used by macrophages to migrate through tissues and sample antigens.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Hammargren, Mark
Acquisition and deployment of the CrimeEye video surveillance system with Genetec video analytics that will allow our security team to maximize their efforts to keep our campus secure by having better situational awareness through enhanced monitoring, verification and validation of threats improving security response times.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Shtanko, Olena
Funded by
Emergence Venture Partners, LLC
The goal is to have immediate impact by identifying prophylactic/therapeutic interventions using micronutrients as effective, low-cost, low-risk countermeasures to reduce viral damage to human airway cells and mitigate virus spread during this pandemic. The impact of our focus on ?epithelial defense? will provide an immediate means to fortify airway epithelial barrier function early during SARS-CoV-2 illness, which will reduce lung water accumulation and dyspnea in infected patients.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Turner, Joanne
Funded by
National Institutes of Health
The major goal of the project is to understand COVID-19 in the elderly for the development of cures or vaccines.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Torrelles, Jordi B
Funded by
Bill & Melinda Gates Foundation
The overall scope of the study is to determine if human monoclonal antibodies (hmAbs) shown in vitro to block SARS-CoV-2 infection are also effective, alone or in combination, in vivo using two rodent animal models of SARS-CoV-2 infection and associated COVID-19 disease.
