As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Martinez-Sobrido, Luis
Funded by
University of Texas Health Science Center at San Antonio
Collaborating Institutions
University of Texas Health Science Center San Antonio
We propose to investigate SARS-CoV-2 and identify key molecular interfaces in RSP complex for their immunogenic disruption. Additionally, we will conduct in vitro and in vivo testing of peptides for immunogenic molecular disruption.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Giavedoni, Luis D.
Funded by
San Antonio Partnership for Precision Therapeutics
The major goal of this study is to develop a vaccine against COVID-19 by creating a recombinant Francisella bacterium that expresses SARS-CoV-2 spike protein.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Schlesinger, Larry S
Funded by
National Institutes of Health
The major goal is to increase primate holding capacity for the P51 base grant.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Dwivedi, Varun
Funded by
Triterpenoid Therapeutics
The major goal is to determine if CDDO-2p-lm inhibits uptake/entry, replication, and release of virus, as well as inhibiting cytopathic effects and excessive inflammation caused by virus (induction of excessive secretion of cytokines, "cytokine storm").
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Daadi, Marcel M
Funded by
National Institutes of Health
The overarching goal of this proposal is to establish the baboon as a relevant model of age-related cognitive impairment by validating behavioral, cognitive, and neuroanatomical features affected in aged baboons and identifying the appropriate miRNA biomarkers that may be causal of the age-related structural and functional changes.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
National Institutes of Health
Collaborating Institutions
University of California Santa Cruz
Our goal is to provide SARS-2-CoV as RNA and as virus in bodily fluids. We will inoculate baboons with 1 X10^6 PFUs intra-nasally. Blood, urine, nasal swabs and feces samples will be taken every two days postinfection. Purified RNA from in vitro cultured virus will also be given for analysis.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Dwivedi, Varun
The major goal is to evaluate antiviral activity of CUSTOMER COMPOUND against SARS-CoV-2 in Vero cell lines.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Torrelles, Jordi B
Funded by
Airway Therapeutics
The goal is to determine the effectivity of AT-100 post-infection in blocking SARS-CoV-2 infectivity.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Martinez-Sobrido, Luis
Collaborating Institutions
University of Rochester
Dr. Martinez-Sobrido will be responsible for the pandemic research plan that includes pre-pandemic risk assessment and emergency pandemic response plan.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Martinez-Sobrido, Luis
Funded by
University of Texas Health Science Center at San Antonio
Collaborating Institutions
University of Texas Health Science Center San Antonio
We hypothesize that SARS-CoV-2 RNA viral mediated infection impacts cardiomyocyte mitochondrial function that results in cardiomyopathy, heart failure, and high mortality.
