The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Gamblin, Truman
Funded by
NIH Natl Inst on Aging
This research project will compare the strains we generate with those we purify from AD and AD related neurodegenerative disorders such as progressive supranuclear palsy. If we are successful in identifying an artificial disease-relevant strain. we will continue our screening efforts to identify disease-relevant tau aggregation inhibitors while simultaneously working toward building a library of tau aggregate strains for multiple neurodegenerative tauopathies. These efforts will not only greatly increase the probability of generating effective therapeutics.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Pozzi, Luca
Funded by
UTSA VPR Office
The aim of this pilot study is to investigate adaptations to unpredictable environments in nocturnal galagos (Galagidae). Animal species may develop adaptive coping mechanisms to improve fitness in environments with unpredictable changes in climate extremes (e.g. El Ni??o). Gummivory - feeding on the gum and sap of woody plant species - is thought to be an adaptive strategy that may have evolved in response to these sudden unpredictable environmental changes. This research will be conducted on Bioko Island. Equatorial Guinea. Bioko is a biodiversity ???hotspot???
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Frantz, Douglas
McHardy, Stanton
Funded by
Texas Biomedical Research Institute
This collaborative research project aims to make transformative advances to combat COVID-19/SARS-CoV-2 and other potentially emerging coronaviruses. The COVID-19 is an ongoing pandemic with 577.547 cases resulting in 26.447 deaths as of March 27. 2020. The strikingly high death rate (17%) among all closed cases (157.112) makes the SARS-CoV-2 the deadliest virus in recent history. SARS-CoV-2 is an enveloped. positive-sense single stranded RNA beta-coronavirus with very large and complex RNA genome. The RNA processing is essential to its survival in a host cell.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
McHardy, Stanton
Wang, Hua-Yu
Funded by
Texas Tech University Health Sciences Center (739)
The Center for Innovative Drug Discovery (CIDD) will provide Dr. Min Kang at Texas Tech Health Science Center with medicinal chemistry support to perform custom synthesis and SAR study of narciclasine and strophanthindin analogs. as well as the derivatives of high-throughput screening hit Life Chemical E10 chemotype. The CIDD will provide all the necessary services. qualified personnel. materials. equipment and the facilities to ensure the requested tasks are completed. The requested tasks may include the following activities: developing synthesis methods. optimizing reaction conditions.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Wang, Yufeng
Cai, Hong
Funded by
Texas Biomedical Research Institute
Over the last three months. COVID-19 has emerged as a major pandemic. SARS-CoV-2. the causative agent of COVID-19. has remarkable infectiousness and pathogenicity. particularly in causing acute respiratory distress syndrome (ARDS) in the elderly and people with immunocompromising conditions.1 The CDC have reported that 8 out of 10 deaths reported in the US related to COVID-19 are in adults 65 years and older. Similar to many other pulmonary infectious diseases.
