The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Salmon, Adam
Funded by
NIH-NATIONAL INSTITUTE ON AGING
In response to RFA-AG-17-040, ?Short-term Measurements of Physical Resilience as aPredictor of Healthspan in Mice?, we propose testing primary fibroblast resilience with a panel ofdifferent cellular insults as a means to predict individual mouse longevity and healthspan. As outlinedby the funding announcement for this RFA, there is a need to develop these standardized tests foruse among the aging community to accelerate research towards revealing mechanisms that underlythe physiological decline of aging.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Minervini, Vanessa
Funded by
NIH-NATIONAL INSTITUTE ON DRUG ABUSE
Prescription opioids (mu opioid receptor agonists) are the drugs of choice for treating moderate to severe pain,despite well-documented adverse effects of those drugs (e.g., abuse, respiratory depression) and significantpublic health concerns. Mu opioids are the most widely abused of all prescription medications and fataloverdoses have reached epidemic levels. Thus, there is a dire need for more effective treatments for pain withfewer deleterious effects.
