The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Chen, Chu
Funded by
NIH-NATL INSTITUTE OF MENTAL HEALTH
The long-term goal of this research project is to understand cellular, molecular, and epigenetic mechanisms ofendocannabinoid (eCB) signaling that may modulate synaptic and neurocognitive functions. While the eCBsystem is known to play an important role in regulation of brain homeostasis, accumulated informationsuggests that the eCB system is also involved in several mental and neurological disorders. Augmentation ofeCB signaling by inhibition of eCB metabolism has been proposed as a promising therapy for treatment andprevention of mental and neurocognitive illnesses.