The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Patterson, Thomas F
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
Collaborating Institutions
UCLA
This contract provides for the development and standardization of animal models for infectious diseases, and may include efficacy testing of candidate products.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Kraig, Ellen B
Funded by
NIH-CHILD HEALTH & HUMAN DEVELOPMENT
Collaborating Institutions
Loyola Wyoming
Poor maternal nutrition and obesity during pregnancy have been associated with a higher incidence ofchronic diseases including cardiovascular disorders, childhood asthma and diabetes. Many of thesecomplications could be due to common underlying immune deficits elicited in utero by a high fat diet (HFD)and/or complications of the mother's obese state. This will be investigated using a nonhuman primate(NHP) model whereby baboons are fed a high calorie/high fat diet (HFD) prior to breeding, duringpregnancy and lactation.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Singh, Brij B
Funded by
NIH-DENTAL & CRANIOFACIAL RESEARCH
Saliva performs a number of extremely important biological functions that are instrumental in maintaining oralhealth. It has been estimated that more than 5 million people in the US suffers from salivary gland dysfunction(Sjogren's syndrome). Although no genes mutations have been identified that could explain the pathogenesisof Sjogren's syndrome (SS), recent evidence have suggested that T17-cell infiltration and induction ofapoptosis in salivary gland acinar cells could be the two major events that could lead to salivary glanddestruction.