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Bacterial infection is a frequent complication among trauma and surgical patients, both civilian and military.  The rate of infectious complications in the U. S. military is approximately 35 percent for combat casualties.  The lack of a rapid diagnostic platform for the detection of bacterial and fungal infections in combat wounds result in mortality and extended stays in Intensive Care Units. The methods currently available are time consuming, lack sensitivity, require specialized equipment, and highly trained personnel.

Naval Medical Research Unit San Antonio (NAMRU-SA)
John Simecek, D.D.S., M.P.H.

Placements of dental resins often result in recurrent caries (cavities) and have higher failure rates compared to amalgam.  Newly developed dental materials that have excellent strength and durability, as well as anticariogenic activity should make resin composites a durable alternative to amalgam. Thus, the addition of visible light activated nanoparticles into novel resin formulations may improve the physical and antibacterial performance of dental resins.

Naval Medical Research Unit San Antonio (NAMRU-SA)
Amber Mallory, Ph.D.