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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

Synergy of cyclic mechanical stress and atherosclerotic environment induces Nitinol stent corrosion

Applied Research

The University of Texas at San Antonio
Hai-Chao Han; Brendy Rincon Troconis
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INVESTIGATING THE ROLE OF TRANSPOSABLE ELEMENT DYSREGULATION AS A DRIVER OF NEUROTOXICITY IN TAUOPATHY

Transposable elements, known colloquially as ?jumping genes,? constitute approximately 45% of the humangenome. Cells utilize epigenetic defenses to limit transposable element jumping, including formation of silencingheterochromatin and generation of piwi-interacting RNAs (piRNAs), small RNAs that facilitate clearance oftransposable element transcripts. Transposable element activation has recently been identified as a keymediator of neuronal death in tauopathies, a group of neurodegenerative disorders that are pathologicallydefined by deposits of tau protein in the brain.

UT Health San Antonio
Frost, Susan Elizabeth
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