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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

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Top viewed research performed by San Antonio Bioscience Organizations

ROLE OF OXIDIZED OMEGA-6 FATTY ACID METABOLITES IN DIABETIC NEUROPATHY

Type 2 diabetes (T2D) afflicts nearly 30 million individuals in the US, with at least 50% suffering from neurologicalcomplications that comprise diabetic neuropathy (DN). The metabolic changes in T2D produce substantialperipheral nerve damage that manifests commonly as debilitating numbness and neuropathic pain. Progressionof the nerve damage often leads to loss of sensation that can compromise patients? ability to execute daily tasksand care for themselves, while also increasing risk of severe injury.

UT Health San Antonio
Lococo, Peter
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Linking receptor-mediated phagocytosis and cAMP pathways in macrophage responses to tuberculosis

In 2017, an estimated 10 million people developed TB disease, demonstrating an urgent need for new approaches to therapy, including host-directed therapy (HDT), to halt infection and progression of active TB. To this end, the overall goal of our ongoing research program is to identify intracellular ?master regulators? of inflammation and metabolic intermediates that dictate human macrophage responses to Mycobacterium tuberculosis infection as a strategy to identify potential host cell targets for HDT.

Texas Biomedical Research Institute
Leopold Wager, Chrissy M
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