The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Natarajan, Mohan
Funded by
NIH-OFFICE OF THE DIRECTOR
We are requesting funds to purchase a SARRP image-guided x-ray platform in order to continually support atotal of 26 research projects. Among the currently funded projects that requires the use of the irradiator, nine ofthem are NIH RO1, one PO1 and one U-42 projects. Additionally, one funded FDA approved phase1/2 study andfour NIH RO1 projects that are likely to get funded (currently under council review) proposed to use theirradiator.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Ebrahimi, Diako
Funded by
National Institutes of Health
We have discovered that human APOBEC3 genes produce enzymes with different sizes and activities in different human populations. Importantly, the mutations induce, by APOBEC3 enzymes, in the HIV-1 genome also have distinct patterns in different human populations. The major goals of this study are to establish association between genetic variations in the APOBEC3 locus and variations in HIV-1 hypermutation patterns, and determine the underlying molecular mechanisms.
