The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Lamb, Audrey
Funded by
NIH Natl Inst General Medical Sci
This basic science research will lay the necessary foundation for future novel antimicrobial drug design efforts. Opine metallophores are recently identified novel metal acquisition small molecules made by diverse bacterial pathogens: Staphylococcus aureus. Pseudomonas aeruginosa. and Yersinia pestis. The operons for biosynthesis. export and re-uptake have only been reported in the last two years. and yet these systems have already been shown to be linked to pathogenesis in mouse models for bacteremia. lung infections and burn wound infections.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Shtanko, Olena
Funded by
Wellcome Trust
Collaborating Institutions
Intervir RX
Assess 2 compounds for antiviral activity in a cell-based coronavirus infection assay.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Department of Defense
Collaborating Institutions
Battelle Memorial Institute
The goal of this study is to investigate the immunogenicity and efficacy of Profectus BioSciences rVSVN4CT1-vectored trivalent (EBOV, SUDV and MARV) filovirus vaccine against an Intramuscular (IM) EBOV challenge in nonhuman primates (NHPs) when administered at various dose schedules. This supplement will only encompass report writing.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Frantz, Douglas
McHardy, Stanton
Funded by
Texas Biomedical Research Institute
This collaborative research project aims to make transformative advances to combat COVID-19/SARS-CoV-2 and other potentially emerging coronaviruses. The COVID-19 is an ongoing pandemic with 577.547 cases resulting in 26.447 deaths as of March 27. 2020. The strikingly high death rate (17%) among all closed cases (157.112) makes the SARS-CoV-2 the deadliest virus in recent history. SARS-CoV-2 is an enveloped. positive-sense single stranded RNA beta-coronavirus with very large and complex RNA genome. The RNA processing is essential to its survival in a host cell.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
McHardy, Stanton
Wang, Hua-Yu
Funded by
Texas Tech University Health Sciences Center (739)
The Center for Innovative Drug Discovery (CIDD) will provide Dr. Min Kang at Texas Tech Health Science Center with medicinal chemistry support to perform custom synthesis and SAR study of narciclasine and strophanthindin analogs. as well as the derivatives of high-throughput screening hit Life Chemical E10 chemotype. The CIDD will provide all the necessary services. qualified personnel. materials. equipment and the facilities to ensure the requested tasks are completed. The requested tasks may include the following activities: developing synthesis methods. optimizing reaction conditions.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Wang, Yufeng
Cai, Hong
Funded by
Texas Biomedical Research Institute
Over the last three months. COVID-19 has emerged as a major pandemic. SARS-CoV-2. the causative agent of COVID-19. has remarkable infectiousness and pathogenicity. particularly in causing acute respiratory distress syndrome (ARDS) in the elderly and people with immunocompromising conditions.1 The CDC have reported that 8 out of 10 deaths reported in the US related to COVID-19 are in adults 65 years and older. Similar to many other pulmonary infectious diseases.
