The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Han, Xianlin
Funded by
NIH-NATIONAL INSTITUTE ON AGING
Collaborating Institutions
Boston University
Aging is the strongest known risk factor for Alzheimer's disease (AD), the most common cause ofdementia in older individuals. However, effective AD therapies remain elusive, which underscores the need tobetter understand disease etiology and its co-occurrence with advanced age. Apolipoprotein E (apoE) is amajor lipid carrier in the brain that transports cholesterol and other lipids such as sulfatide (a key component ofmyelin) between brain cells. APOE polymorphic alleles are the main genetic determinants of AD risk (e.g.,APOE4 allele is the strongest genetic risk factor for AD).
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Velligan, Dawn I
Funded by
NIH-NATL INSTITUTE OF MENTAL HEALTH
Collaborating Institutions
Vanguard
Schizophrenia remains one of the most disabling conditions world-wide with an economic burden thatexceeded $155 billion dollars in fiscal year 2013 alone. Despite existing medication and community treatment,many individuals with this diagnosis continue to have poor outcomes and struggle toward recovery.
