As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Schlesinger, Larry S
Funded by
National Institutes of Health
The major goal is to increase primate holding capacity for the P51 base grant.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Dwivedi, Varun
Funded by
Triterpenoid Therapeutics
The major goal is to determine if CDDO-2p-lm inhibits uptake/entry, replication, and release of virus, as well as inhibiting cytopathic effects and excessive inflammation caused by virus (induction of excessive secretion of cytokines, "cytokine storm").
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
National Institutes of Health
Collaborating Institutions
University of California Santa Cruz
Our goal is to provide SARS-2-CoV as RNA and as virus in bodily fluids. We will inoculate baboons with 1 X10^6 PFUs intra-nasally. Blood, urine, nasal swabs and feces samples will be taken every two days postinfection. Purified RNA from in vitro cultured virus will also be given for analysis.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Dwivedi, Varun
The major goal is to evaluate antiviral activity of CUSTOMER COMPOUND against SARS-CoV-2 in Vero cell lines.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Torrelles, Jordi B
Funded by
Airway Therapeutics
The goal is to determine the effectivity of AT-100 post-infection in blocking SARS-CoV-2 infectivity.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Giavedoni, Luis D.
Funded by
San Antonio Partnership for Precision Therapeutics
The major goal of this study is to develop a vaccine against COVID-19 by creating a recombinant Francisella bacterium that expresses SARS-CoV-2 spike protein.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Principal Investigator(s)
Dr. Kenneth Carson
Funded by
San Antonio Partnership for Precision Therapeutics
Collaborating Institutions
South Texas Center for Emerging Infectious Diseases
UT Health San Antonio
Texas Biomedical Research Institute
The San Antonio Partnership for Precision Therapeutics has awarded $200,000 for a collaborative study to develop a novel vaccine to combat COVID-19. Within days of the Stay Home/Work Safe directive issued by the City of San Antonio, the San Antonio Partnership for Precision Therapeutics (SAPPT) organized and issued a call for proposals to combat COVID-19.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Leopold Wager, Chrissy M
M. tuberculosis, which causes the worldwide global health problem tuberculosis (TB), is transmitted human to human via the airborne route into lung alveoli and ultimately exploits and grows in host macrophages. We seek to understand the cell signaling pathways initiated by infection of human macrophages with M. tuberculosis that lead to disease. Increased understanding of how macrophages are susceptible to M. tuberculosis is expected to aid in the development of host-directed therapies for TB.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Martinez-Sobrido, Luis
Funded by
University of Texas Health Science Center at San Antonio
Collaborating Institutions
University of Texas Health Science Center San Antonio
We hypothesize that SARS-CoV-2 RNA viral mediated infection impacts cardiomyocyte mitochondrial function that results in cardiomyopathy, heart failure, and high mortality.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Regeneron Pharmaceuticals, Inc.
The purpose of this project is to test monoclonal antibodies in a neutralization assay with SARS-CoV-2 virus to generate IC50 values.