The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Webster, Phillip Justin
Funded by
NIH
The Effects of Chronic mTOR Inhibition on Aging Muscle and Mitochondrial Function Sarcopenia is the age-dependent loss of skeletal muscle mass and function that begins early in adulthood and progresses into old age. These losses can increase the incidence of falls, morbidity, and severely impair the well-being of older people. The current therapies are insufficient to reverse these losses, so identifying key pathways could open up new therapeutic options which is particularly pressing given the rapid increase in the population of older people with the aging of the Baby Boom generation.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Lafer, Eileen M.
Funded by
NIH
Protein and membrane trafficking depends on choreographed reactions which deform membranes and sequentially assemble and disassemble protein complexes. Hsp70s--the ubiquitous chaperones involved in protein folding and many cellular protein processing reactions--function as motors in trafficking processes such as translocation of proteins into ER and mitochondria, and disassembly of the clathrin coats that form around nascent endocytic vesicles.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Principal Investigator(s)
Daniel P. Nicolella, Ph.D.
Kase Saylor
Funded by
Southwest Research Institute
The science of elite human performance is evolving at a rapid pace as researchers tap into data from the human body to reveal the complex roles of sleep, nutrition, genetics, training, and neuroscience in the performance of the world’s top athletes. SwRI's Human Performance Initiative (HPI) applies a multidisciplinary scientific and engineering approach to better understand and quantify the complex biomechanical and physiological components of physical performance.
