Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Principal Investigator(s)
Dr. Jonathan Bohmann
Funded by
Medical CBRN Defense Consortium
Collaborating Institutions
University of Pittsburgh
Defense Threat Reduction Agency
Medical CBRN Defense Consortium
Southwest Research Institute has received funding from the Medical CBRN Defense Consortium (MCDC) administered by Advanced Technology International to develop a nerve agent antidote for emergency use on the battlefield or to protect public health.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Principal Investigator(s)
Dr. Shawn Blumberg
Funded by
SwRI internal funding
Collaborating Institutions
Texas Biomedical Research Institute
Drug discovery software at Southwest Research Institute is expanding the capacity to virtually screen drug compounds for possible treatment of coronavirus and other infectious diseases.
SwRI’s Rhodium™ virtual screening tool recently evaluated 2 million drug compounds in a few days, hoping to identify high-probability drugs that may have efficacy against the coronavirus with minimal adverse side effects. Institute scientists initiated the molecular modeling research with SwRI internal funding.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Ivanov, Dmitri N
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
SAMHD1, a mammalian member of the HD-domain hydrolase family of enzymes, catalyzes hydrolysis ofdeoxynucleotides triphosphates (dNTPs) to triphosphate and unphosphorylated nucleosides, which is thoughtto be the main pathway for controlled depletion of cellular dNTPs. Discoveries that SAMHD1 is an immunefactor that restricts retroviral replication in non-cycling immune cells and regulates interferon signaling revealedthat dNTP depletion may act as a defense mechanism of innate antiviral immunity.
59th Medical Wing at the Wilford Hall Ambulatory Surgical Center (WHASC)
The 59th Medical Wing Chief Scientist provides the strategic vision, direction, oversight, project management support and technical resources to advance medical modernization efforts with a unique focus on research activities.
