1.SCOPE.This research project processes experimental testing and characterization of suction devices for Excitus AS by Dr. R. Lyle Hood of the Mechanical Engineering Department at the University of Texas at San Antonio (UTSA) and Robert De Lorenzo of the Emergency Medicine Department at the University of Texas Health Science Center in San Antonio.

This proposal addresses developing advanced airway devices for use during respiratory failure and prolonged intubation to deliver therapeutics during intubation for acute respiratory distress syndrome. In a broader context. controlled therapeutic delivery from our endotracheal tube platform may serve a larger role in preventing and treating ventilator associated pneumonia. Our novel ET tube coating provides the additional potential of drug delivery. We propose to employ our existing. novel laryngotracheal models delivering therapeutics to vocal folds.

This research will be carried out via the training and mentoring of a graduate student in the joint graduate program in biomedical engineering to promote activities ongoing in the Extracorporeal Life Support capability area.Autonomous Reanimation and Evacuation Research to include the development. application and validation of extracorporeal life support devices.

The outcomes of this research project provide opportunities to overcomes some of the challenges in successful translation of animal data into practical applications for humans such as predicting TBI and developing appropriate design criteria for impact sensor technology and protective equipment. In this project. we also develop axonal injury thresholds for repeated TBI for the first time. 
 
 
 Abstract: 
 Traumatic brain injury (TBI). particularly mild-TBI/ concussion.

Applied Research

Applied Research

Basic Research

Basic Research

Basic Research

Development Research