59th Medical Wing at the Wilford Hall Ambulatory Surgical Center (WHASC)
The 59th Medical Wing Chief Scientist provides the strategic vision, direction, oversight, project management support and technical resources to advance medical modernization efforts with a unique focus on research activities.
Naval Medical Research Unit San Antonio (NAMRU-SA)
Located in South Texas on the San Antonio, Military Joint Base complex, the Naval Medical Research Unit San Antonio (NAMRU-SA) is one of eight subordinate research commands in the global network of laboratories operating under the Naval Medical Research Center, Silver Spring, MD.
Principal Investigator(s)
Jonathan Stahl, D.D.S., Ph.D.
Funded by
U.S. Navy Bureau of Medicine and Surgery (BUMED) http://www.med.navy.mil/Pages/Default.aspx
Battlefield wounds present a unique challenge due to extended evacuation times and unique infection that often complicate the healing process. Currently traditional bandages are used on the battlefield to dress wounds. They provide a physical barrier and help to control hemorrhage but do not actively aid in the healing process. Navy researchers are working to create bandages with bioactive components such as growth factors, antibiotics and other agents that may enhance healing rates and reduce scar formation.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Huang, Tim H.-M.
Funded by
NIH
DNA hypermethylation of promoter CpG islands is known to be associated with transcriptional silencing in endometrial cancer. We recently identified a unique set of CpG island loci that are hypermethylated in non- recurrent tumors but coordinately hypomethylated (or less methylated) in primary tumors that subsequently recurred. The loci can be highly susceptible to de novo DNA methylation (i.e., a default state) partly attributed to the high expression of DNA methyltransferase 1 (DNMT1) and Polycomb Repressor Complex 2 (PRC2).
