The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Carreno, Flavia R
Funded by
NIH-NATL INSTITUTE OF MENTAL HEALTH
Even though ketamine has been heralded as a significant advance in the development of novel and rapidtreatments for depression, the acute psychotomimetic and reinforcing effects of this drug limit its utility.Previously, we demonstrated that activation of a circuit from the ventral hippocampus to the medial prefrontalcortex is both necessary and sufficient for ketamine?s sustained antidepressant-like effects in rats.
