Novel model for studying PDAC using normal human pancreatic tissue For the past twenty years, the survival rate for many cancers has improved, but survival for pancreaticductal adenocarcinoma (PDAC) has not, due to lack of both early detection methods and effective treatments.Human PADC cancer cell lines have been widely used. However, such cell lines are far from original organtissue, and their highly unstable genome complicates interpretation.