As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Ross, Corinna
The goal of this project is to guide the investigation of the effects of the experimental drug on male fertility in male marmosets. Marmoset fertility will be assessed via sperm collection and testicular biopsy to determine whether the drug effectively ends the production of live sperm.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Southwest Research Institute
The primary objective of this project is to identify drug compounds that may inhibit SARS-CoV-2 replication in an in vitro tissue culture assay. Vero E6 cells will be used to evaluate the effectiveness of the test articles to inhibit SARS-CoV-2 replication.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Wang, Hua-Yu
Funded by
4E Therapeutics, Inc.
Through this research project. The CIDD will work closely with 4E Therapeutics to prepare a sufficient number of structural analogs to support the goals of the research.The CIDD will provide synthesis support to 4E Therapeutics to prepare and characterize compounds to support the program goals.All novel compound design.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Macpherson, Lindsey
Funded by
UTSA VPR Office
Brain Health Topic: Vagal signaling between the gut and the CNS contributes to appetite regulation. inflammation and immune responses. gastrointestinal motility. nausea. emesis. and even mood1-6 . Therefore. vagal neurons are an attractive target for medical interventions. Since vagal signaling may be modulated within the digestive tract. drugs need not cross the blood-brain barrier. reducing potential side effects and toxicity. To eventually identify potentially drug-able targets within the vagus to improve mental and digestive health.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Mohan, Mahesh
The proposed studies is aimed at understanding the molecular mechanisms underlying oral mucosal dysfunction and developing novel immune
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
McHardy, Stanton
Funded by
Univ of TX HSC at San Antonio 745
The systemic inflammatory response in sepsis has devastating consequences resulting in high morbidity and mortality. Over the past decade. mortality from sepsis alone has remained greater than 25%. despite effective antimicrobial therapy. In particular. the survival rate of the Hispanic population with other complications and combat casualties are often poorer. This highlights lack of understanding of the pathways operative in sepsis and the necessity for improved therapies. One of the major changes that occur during Multi-organ-failure (MOF) in severe sepsis is mitochondrial dysfunction.
