As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Daadi, Marcel M
Collaborating Institutions
University of California Irvine
Major Goal: The goal of this grant application is to produce clinical grade human neural stem cells from embryonic stem cells and to demonstrate their long-term safety and efficacy in a rodent and a nonhuman primate model (marmoset) of acute focal traumatic brain injury (TBI).
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Ebrahimi, Diako
Funded by
William & Ella Owens Medical Research Foundation
Our DNA contains many sequences of ancient viral origin. Activation of these viruses can trigger components of our immune system such as APOBEC3 enzymes, which in turn can induce DNA mutation and damage. We aim to use a combined computational/experimental approach to reveal the role of our internal viral sequences in cancer mutations.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Mohan, Mahesh
Identify epigenetic mechanisms associated with monocyte/microglia activation associated with HIV associated neurocognitive disorder using the SIV-rhesus macaque model. In addition, we will use cannabinoids to suppress inflammation and determine the epigenetic mechanisms underlying its anti-inflammatory effects.
