The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Musi, Nicolas
For the past three decades, the University of Texas Health Science Center at San Antonio (UTHSCSA) hashosted a premier Training Program in the biology of aging that has resulted in the development of a newgeneration of leaders in this field. This application seeks to continue this T32 Training Program and we requestfunds to support four predoctoral and four postdoctoral trainees.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Chen, Chu
Funded by
NIH-NATIONAL INSTITUTE ON AGING
Alzheimer's disease (AD) is the most common cause of dementia in the elderly and a majority of AD cases issporadic without known causes. While the etiology of AD is multifactorial and complex, growing evidencesuggests that traumatic brain injury (TBI) is a risk factor for development of AD and dementia. Repetitive TBIcauses chronic traumatic encephalopathy (CTE), a progressive neurodegenerative disease. Pathological TDP-43 inclusions are one of the important hallmarks of neuropathology in CTE.
