The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Flores, Shahida K
Funded by
NIH-GENERAL MEDICAL SCIENCES
Endocytosis is a conserved pathway that internalizes macromolecules and transmembrane proteins and sortsthem through the endo-lysosomal system to their destinations. This process is often dysregulated in manydiseases including cancers, metabolic disorders and neurodegenerative diseases. Elucidating the endocyticmechanisms of transmembrane proteins will improve our understanding of biological processes, diseaseprognosis and therapeutic strategies.
BioBridge Global is a San Antonio, Texas-based nonprofit corporation that offers diverse services through its subsidiaries – the South Texas Blood & Tissue Center, QualTex Laboratories, GenCure and the Blood & Tissue Center Foundation.
Principal Investigator(s)
Scott Jones,
Anand Srinivasan
Development of new analytical assays which determine the potency of human mesnenchymal stromal cells and other cells utilized for cell therapies.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Zang, Mengwei
Funded by
NIH-DIABETES/DIGESTIVE/KIDNEY DISEASES
The major goal of this project is to understand how the NAD+-dependent deacetylase SIRT1 regulateshepatokines that are secreted by the liver and how this process slows the progression of non-alcoholic fatty liverdisease (NAFLD) and obesity. Obesity or being overweight affects approximately 70% of U.S. adults andincreases the prevalence of developing NAFLD and Type 2 diabetes. Type 2 diabetes is a life-threateningdisease characterized by peripheral insulin resistance, which dysregulates inter-tissue communication topromote hyperglycemia and dyslipidemia.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Sung, Patrick M
Funded by
NIH-ENVIRONMENTAL HEALTH SCIENCES
Exposure of cells to environmental agents, such as radiation, heavy metals, air pollutants andmutagenic chemicals, generates DNA double-strand breaks (DSB)s and other chromosomallesions, and can also cause replicative stress.
