The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Brenner, Andrew
Glioblastoma (GBM) is the most common and most aggressive of the primary malignant brain tumor in adults,with a median overall survival of 19.6 months following multi-modality therapy. The main limiting factor indelivering a tumoricidal radiation dose is the toxicity to surrounding brain. Therapeutic radionuclides, due to ashort tissue path and differences in radiobiology, have the potential to extend the therapeutic window for radiationin GBM.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Hiroi, Noboru
Funded by
NIH-NATL INSTITUTE OF MENTAL HEALTH
Cognitive deficits are major disabling impairments associated with autism and schizophrenia. Because theunderlying genetic and cellular mechanisms of such deficits are still poorly understood, mechanism-basedtherapeutic options do not exist, limiting the effective integration of patients into society. Previous clinical workhas shown that executive functions such as working memory and cognitive flexibility start to lag behind fromadolescence to adulthood in individuals with autism and schizophrenia.