Stimulant abuse is a serious public health problem with untold medical, societal, and economic impactworldwide. Despite decades of research into the neurobiology of drug abuse, there are no FDA-approvedpharmacotherapies for stimulant abuse. One strategy to reduce the time required to get candidate medicationsinto the clinic is to repurpose drugs, already approved by the FDA for other indications, to treat stimulant abuse,and one strategy to improve the therapeutic effectiveness of a drug is to administer it in combination with seconddrug with a complimentary mechanism of action.
