18-150 The goal is to send inactivated Zika virus infection of marmosets for analysis using nanotechnology. Role: Sub PI

The role of macrophage nuclear receptors in tuberculosis.

The primary objective of this study is to assess the treatment patterns, response rates, progression free survival and overall survival among patients diagnosed with MCL initiating novel therapies.

The primary objective of this study is to compare the overall survival (OS) following treatment with BGB-A317 vs. investigator chosen chemotherapy (ICC) when given as second line treatment in patients with advanced unresectable/metastatic esophageal squamous cell carcinoma (ESCC).

Objective: Analyze doramectin levels in serum samples from cattle treated in the field to study the interaction between a 1% doramectin product and Bm86 vaccination against fever ticks. Approach: Blood samples collected during the field study will be processed at the USDA, ARS, Cattle Fever Tick Research Laboratory (CFTRL) to obtain serum. ARS will provide the serum samples to The University of Texas at San Antonio (UTSA) to conduct the analysis per the one year field study as detailed below. The serum samples will be shipped to UTSA for analysis to determine doramectin levels.

Objective:

Complete concentration analysis of eprinomectin in serum obtained from blood samples collected at the USDA, ARS, Cattle Fever Tick Research Laboratory (CFTRL) in collaboration with the ARS scientists in support of the continuation of research studying the interaction between the Bm86 vaccine and a long-acting eprinomectin injectable formulation.

Approach:

HIV is a major worldwide challenge that remains to be solved, and there is a continuous need to identify improved preventative and therapeutic interventions. This annual symposium provides an environment that promotes the exchange of ideas and perspectives, and fosters new collaborations, especially between junior and senior members of the research community.

Obesity is a global epidemic; nearly 60% of women of reproductive age are considered overweight or obese in the U.S.. and this percentage is continuously rising. The prevalence of childhood obesity is increasing at alarming rates. and children born from obese mothers have higher risks of developing diabetes. metabolic syndrome. and cardiovascular diseases. Compelling evidence from various species indicates that maternal obesity negatively influences the metabolic health of offspring and impacts various systems; however.

Enterohemorrhagic Escherichia coli (EHEC) of the O157:H7 serotype are notorious for the producing
 highly potent Shiga toxin. which is a direct mediator of life-threatening global human disease. In this proposal.

Overview: Lorisiform primates represent almost 10% of the living primate species; however, their taxonomy, evolutionary history, and biogeography are still poorly understood. Indeed, a major limitation to investigations of primate evolutionary history is the ability to obtain high quality genetic data across the entire geographic distribution of a taxon. Low quality samples, lack of geographic resolution, and access to wild populations have been some of the many limitations that have negatively impacted the field of primate phylogenetics.