The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Yeh, Chih-Ko
Funded by
NIH-DENTAL & CRANIOFACIAL RESEARCH
Collaborating Institutions
UTSA
Saliva is an important defense mechanism for protecting oral health. Salivary gland (SG) hypofunctionresults in uncontrolled and severe oral diseases that lead to severely compromised quality of life. SGsare highly differentiated and have little regenerative capacity once they are destroyed by therapy ordisease (e.g. radiation therapy or autoimmune Sjgren?s syndrome). Therefore, the development ofstrategies for preserving or regenerating the secretory function of SGs is essential for successfulmanagement of these patients.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Figure 1: Novel SwRI-developed bead-free and perfusion-based, closed-loop T-cell manufacturing system using an SwRI-proprietary 3D bioreactor.