As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Fisher BioServices
TxBiomed will furnish the necessary services, qualified personnel, material, equipment and facilities to perform vaccine testing using the Sudan GP virus.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Hayhurst, Andrew
Funded by
NIH-PMS
Mining recombinant antibody libraries for binders that function well together in an immunoassay is a critical component of developing diagnostics for infectious disease agents and assays for host biomarkers to study disease processes. While identifying antibodies that bind the antigen of interest is reasonably straightforward, combining them in a sandwich assay demands protein purification and in vitro modification, processes that rapidly escalate costs and time when pairing hundreds of potential clones.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Gauduin, Marie-Claire E.
Funded by
UTHSCSA
The goal of this project is to piece together an effective HIV vaccine using the Simian Immunodeficiency Virus and the Varicella virus.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
SIGA Technologies
The goal of the program described here is to develop an antiviral drug for treating and preventing Lassa fever and other hemorrhagic fevers of arenavirus origin.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Anderson, Timothy J. C.
Funded by
UTHSCSA
Malaria is major public health problem, causing over 1 million deaths per year worldwide. The discovery and development of new antimalarial drugs is becoming increasingly urgent as drug- resistant strains become increasingly prevalent. We propose to isolate the active antimalarial compound(s) present in the crude extracts in at least 14 previously uninvestigated plants that have promising antimalarial activity.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Giavedoni, Luis D.
Funded by
NIH-PMS
HIV and AIDS represent a critical threat to public health in the United States and internationally. This annual symposium contributes to expanding the knowledge base that will ultimately result in a vaccine to prevent transmission of HIV and treatments for those currently living with AIDS.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Giavedoni, Luis D.
Funded by
Yale University
STDs and unwanted pregnancy create tremendous burdens on individuals, on U.S. society, and on the national health care costs. The work in this project will provide new approaches for preventing and treating STDs and preventing unwanted pregnancy. Specifically, we will test a new approach for treatment of HIV/AIDS infections. The approach will emphasize materials and approaches that can be translated into clinical products, which would provide new opportunities for enhancing health.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
Battelle
The mission of the TxBiomed component is to generate the Marburg virus and propagate it, determine the virus' consensus sequence, experimentally determine the LD50 of guinea pig adapted Angolan Marburg virus, and evaluate the immunogenicity and efficacy of Marburg and Ebola Zaire VLPs monovalent vaccines when administered in two different adjuvants to guinea pigs and Non-Human Primates.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Anderson, Timothy J. C.
Funded by
NIH-PMS
Collaborating Institutions
University of Notre Dame
Gene copy number variation (CNV) is ubiquitous in eukaryotic genomes and the resultant dosage changes can play an important role in determining phenotype. We aim to define the extent, evolutionary dynamics and functionality of CNV in the malaria parasite genome (Plasmodium falciparum). To achieve this we will use comparative genomic hybridization (cGH) which provides an efficient tool for assaying both CNV and single nucleotide polymorphism (SNP) and is particularly effective in haploid genomes.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Fisher BioServices
TxBiomed will furnish the necessary services, qualified personnel, material, equipment and facilities to perform vaccine testing using the MVA-BN-Marv vaccine against 3 viruses.