As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Shtanko, Olena
Funded by
National Institutes of Health
Collaborating Institutions
Fox Chase Chemical Diversity Center Inc
This is to do one mouse experiment to evaluate a small molecule inhibitor.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Jean Patterson
Mark Gorelik
Funded by
San Antonio Medical Foundation
Collaborating Institutions
UTHSCSA; UTSA
This project seeks to find novel molecular parameters of disease in Kawasaki disease. We will collaborate with UTSA and UTHSCSA for help with proteomic analysis and mouse echocardiograms. Using proteomics, we will correlate histologic disease and cardiac function with protein signatures of disease. This is a 1 year project.
Southwest Research Institute (SwRI), headquartered in San Antonio, Texas, is one of the oldest and largest independent, nonprofit, applied research and development (R&D) organizations in the United States.
Principal Investigator(s)
Dr. Shawn Blumberg
Funded by
Foundation
Southwest Research Institute® (SwRI®) received a Bill & Melinda Gates Foundation grant of $267,870 to develop new technology to lower the cost of artemisinin, the primary drug used to treat malaria.
59th Medical Wing at the Wilford Hall Ambulatory Surgical Center (WHASC)
The 59th Medical Wing Chief Scientist provides the strategic vision, direction, oversight, project management support and technical resources to advance medical modernization efforts with a unique focus on research activities.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Paladini, Carlos
Norepinephrine (NE) provides excitatory drive onto midbrain dopamine (DA) neurons and modulates responses to dopaminergic drugs, including psychostimulants. Chronic loss of noradrenergic tone impairs DA neuron firing and DA release, leading to compensatory alterations in postsynaptic DA receptor signaling and a paradoxical hypersensitivity to dopaminergic drugs. The goal of this proposal is to identify the molecular and cellular mechanisms underlying the behavioral hypersensitivity to cocaine following chronic inhibition of the NE biosynthetic enzyme, dopamine -hydroxylase (DBH).
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Olena Shtanko
Funded by
NIH
Collaborating Institutions
University of Iowa
We will be responsible for BSL4 experiments involving Ebola virus infection of treated and untreated murine macrophages.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Hsieh, Jenny
Funded by
UTSA VPR Office
The `opioid epidemic' is one of the most significant health issues facing this country today with rates of opioid-associated deaths up 200% since 2000. This epidemic is also taking its toll on pregnant women and their babies, with an annual average of ~21,000 pregnant women ages 15 to 44 who have misused opioids this past month. Infants who have been exposed to opioid drugs exhibit an increased risk of neurological and behavioral consequences.
